By now most everyone practicing Sleep Dentistry has seen or handled a nylon appliance; the Narval by ResMed and the D-SAD by Panthera. These companies have introduced us to a “New World” way of viewing appliances that manage Sleep Apnea; the CAD-CAM 3-D Printer way. Using laser sintering to layer nylon in successive layers the 3D Printer creates the appliance from the inside out. This nylon polymer is quite remarkable to say the least. These appliances are definitely a “Game Changer” and it is worth while becoming familiar with their unique characteristics.